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EMAGIX

Diagnosing diseased blood vessels in the retina and brain

EMAGIX is a software platform that measures retina and brain vascular health

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Measuring the rate of leakage from retinal blood vessels in diseases such as diabetic retinopathy, age-related macular degeneration, and retinal vein occlusion.

To learn more, visit our Retina Health page

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Measuring the rate of leakage from brain blood vessels in conditions such as traumatic brain injury, epilepsy, dementia, depression, and aging.

To learn more, visit our Brain Health page

RETINA PUBLICATIONS

  1. Link Between Baseline Peripheral Vascular Leakage and Treatment Response in Patients with Central Retinal Vein Occlusion: A Pilot Study. 
    Clinical Ophthalmology. 2026.
     

  2. Retinal Vessel Dysfunction in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy.
    Neurology Open Access. 2026.
     

  3. Quantitative Fluorescein Angiography Biomarkers in Diabetic Macular Edema.
    Retina. 2025.
     

  4. Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy.
    Prog Retin Eye Res. 2024
     

  5. Association of Intravenous Fluorescein Angiography and Adaptive Optics Imaging in Diabetic Retinopathy.
    Retina. 2024.
     

  6. Artificial intelligence-based extraction of quantitative ultra-widefield fluorescein angiography parameters in retinal vein occlusion.
    Can J Ophthalmol. 2024
     

  7. Artificial Intelligence-Enhanced Analysis of Retinal Vasculature in Age-Related Macular Degeneration.
    Retina. 2024.
     

  8. A fluorescein angiography-based computer-aided algorithm for assessing the retinal vasculature in diabetic retinopathy.
    Eye. 2023.
     

  9. Angiographic evidence of proliferative retinopathy predicts neuropsychiatric morbidity in diabetic patients.
    Psychoneuroendocrinology. 2016.
     

  10. Novel fluorescein angiography-based computer-aided algorithm for assessment of retinal vessel permeability.
    PLoS One. 2013.

BRAIN PUBLICATIONS

  1. Blood-brain barrier disruption, traumatic encephalopathy, and cognitive decline in retired athletes.
    Science translational medicine 2026.
     

  2. Blood-brain barrier opening as a predictor of epilepsy and mortality after subarachnoid haemorrhage.
    eBioMedicine 2025.
     

  3. Imaging blood-brain barrier dysfunction in drug-resistant epilepsy: A multi-center study.
    Epilepsia 2025.
     

  4. Restoration of blood brain barrier integrity post neurosurgical resection in drug resistant epilepsy.
    Epilepsy & Behavior 2025.
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  5. Blood-brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment.
    Nature neuroscience 2024.
     

  6. Evidence for interictal blood-brain barrier dysfunction in people with epilepsy.
    Epilepsia. 2024.
     

  7. Atypical paroxysmal slow cortical activity in healthy adults: Relationship to age and cognitive performance.
    Neurobiology of Aging. 2024.
     

  8. Cortical Plasticity is associated with Blood-Brain-Barrier Modulation.
    eLife. 2024.
     

  9. ​Quantitative analysis of magnetic resonance images for characterization of blood-brain barrier dysfunction in dogs with brain tumors.
    Journal of Veterinary Internal Medicine. 2023.
     

  10. Neuro-psychiatric symptoms in directly and indirectly blast exposed civilian survivors of urban missile attacks.
    BMC Psychiatry. 2023.
     

  11. Blood-Brain Barrier Dysfunction and Exposure to Head Impacts in University Football Players​.
    Clinical J Sport Medicine. 2023.
     

  12. Reversal of insulin resistance is associated with repair of blood-brain barrier dysfunction and remission in a patient with treatment-resistant bipolar depression.
    Bipolar Disorders. 2022.
    ​​​

  13. Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction.
    Brain. 2022.
     

  14. Blood-brain barrier leakage in systemic lupus erythematosus is associated with gray matter loss and cognitive impairment.
    Ann Rheum Dis. 2020.
     

  15. Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players.
    Brain. 2020.
     

  16. Blood-brain barrier imaging as a potential biomarker for bipolar disorder progression.
    Neuroimage Clinical. 2020.
     

  17. Dynamic Blood-Brain Barrier Regulation in Mild Traumatic Brain Injury.
    J Neurotrauma. 2020.
     

  18. Early blood-brain barrier dysfunction predicts neurological outcome following aneurysmal subarachnoid hemorrhage.
    EBioMedicine. 2019.
     

  19. Blood-brain barrier dysfunction in canine epileptic seizures detected by dynamic contrast-enhanced magnetic resonance imaging.
    Epilepsia. 2019.
     

  20. Blood-Brain Barrier Leakage: A New Biomarker in Transient Ischemic Attacks.
    Stroke. 2019.
     

  21. Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model.
    Brain. 2018.
     

  22. Imaging Blood-Brain Barrier Dysfunction in Football Players.
    JAMA Neurology. 2014.
     

  23. Blood-brain barrier imaging in human neuropathologies.
    Arch Med Res. 2014. 
     

  24. Blood-brain barrier disruption in post-traumatic epilepsy.
    A. J Neurol Neurosurg Psychiatry. 2008.
     

  25. Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II.
    Neurology. 2005.
     

  26. Focal cortical dysfunction and blood-brain barrier disruption in patients with Postconcussion syndrome.
    J Clin Neurophysiol. 2005.

EMAGIX

1344 Summer Street,
Halifax, NS, ​B3H 0A8, Canada
​info@emagix.ca​

©2026 EMAGIX Inc. All rights reserved

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